Packaging Technology

Bosch meets pharmaceutical demand for flexibility GKF 702 and GKF 2500 capsule filling machines

  • Maximum flexibility, modularity and precise dosing
  • GKF 702: Versatile platform is a future-proof investment
  • GKF 2500: Micro dosing with high performance and maximum precision
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  • August 27, 2012
  • Packaging Technology
  • Press releases
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press release

Bosch Packaging Technology demonstrates its expertise in capsule filling machines with the GKF 702 for small and medium-sized batches, along with the high-performance GKF 2500 equipped with a micro dosing station.

“The GKF 702 offers the same flexibility and user-friendly operation as the GKF 701, which has been successful on the market for the past nine years,” explained Product Manager Melanie Beck. The new design offers improved ergonomics and accessibility. Meeting the growing needs in today's pharmaceutical industry for flexibility, the unit can be used in the lab for extremely small batches. Parameters required in future production operations can be comprehensively simulated and defined. “This makes it possible to fill very small batches for pharmaceutical or clinical purposes under realistic production conditions,” Beck added.

Micro dosing of powders is used on the high-performance GKF 2500. “This machine gives customers the ability to handle micro dosing with maximum yield and precision, and minimum deviation from standards,” said Beck.

Flexible solutions for planning reliability and improved availability
The extremely flexible GKF 702 capsule filling machine is suitable for all standard filling techniques. Recently, the portfolio has been enhanced to include dosator technology. For laboratory applications, Bosch developed the so-called “mini-bowl” for small product batches ranging from 100 to 300 milliliters to ensure a higher powder yield. This provides a cost-effective filling solution that is ideal for expensive powders or limited availability during the development phase.
The pellet station enables gentle and precise filling of pellets and can be used in conjunction with other stations for combination products. The liquid station is suitable for thixotropic and hydrophilic liquids that can also be temperature controlled during the filling process. Powder filling is conducted with the proven filling/stamping station. The “slide-gate” system featured on the 1400/2500 series machines is now available for the GKF 702 filling station. This significantly increases batch yield and enables filling of free-flowing granules and pellets. The slide-gate system also increases product flexibility since powder and pellets can be filled on the same station.

The GKF 702 is a future-proof machine. Compatibility with new filling stations is one of the key features of the machine design. For example, the GKF 2500 micro dosing unit is also available for the GKF 702.

Micro dosing on the GKF 2500
Micro dosing refers to filling quantities of less than 30 milligrams. Precise filling of minuscule doses without agglomeration is essential for highly active inhalation products that require exact dosages. This is why Bosch developed a dosing wheel designed for use with highly active inhalation products with quantities ranging from two to 30 milligrams. Micro dosing is suited for application on, for instance, the high-performance machine GKF 2500.

The modular, flexible filling station can also be used for hard-to-fill products. Adjustments can be made as necessary during the filling process without removing the filling roller. This saves time and reduces waste. “The GKF 2500 meets all requirements for pharmaceutical production and offers manufacturers a gentle filling process with need-based application,” said Melanie Beck. Designed to meet future needs, the filling station can be easily assembled and disassembled. The small number of format parts makes machine changeover for a new product faster and easier. The GKF 2500 is suitable for flexible processing of a wider range of products with a higher yield.

Based in Waiblingen near Stuttgart, Germany, and employing 6,200 associates, the Bosch Packaging Technology division is one of the leading suppliers of process and packaging technology. At over 30 locations in more than 15 countries worldwide, a highly-qualified workforce develops and produces complete solutions for the pharmaceuticals, food, and confectionery industries. These solutions are complemented by a comprehensive after-sales service portfolio. A global service and sales network provides customers with local points of contact.

Additional information is available online at www.boschpackaging.com

The Bosch Group is a leading global supplier of technology and services. It employs roughly 375,000 associates worldwide (as of December 31, 2015). The company generated sales of 70.6 billion euros in 2015. Its operations are divided into four business sectors: Mobility Solutions, Industrial Technology, Consumer Goods, and Energy and Building Technology. The Bosch Group comprises Robert Bosch GmbH and its roughly 440 subsidiaries and regional companies in some 60 countries. Including sales and service partners, Bosch’s global manufacturing and sales network covers some 150 countries. The basis for the company’s future growth is its innovative strength. Bosch employs 55,800 associates in research and development at 118 locations across the globe. The Bosch Group’s strategic objective is to deliver innovations for a connected life. Bosch improves quality of life worldwide with products and services that are innovative and spark enthusiasm. In short, Bosch creates technology that is “Invented for life.”

Further information is available online at www.bosch.com and www.bosch-press.com, http://twitter.com/BoschPresse.

PI7772 - August 27, 2012

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