Packaging Technology

Safety, Efficiency and Reliability: Bosch presents new developments for the pharmaceutical process and packaging technology Wolfgang Szczerba, Senior Vice President Business Unit Pharma,
Bosch Packaging Technology

  • at the Achema Press Conference, June 19, 2012
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  • June 19, 2012
  • Packaging Technology
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press release

Thank you very much Mr Klefenz.
Ladies and Gentlemen, I would also like to welcome you here today. In the run up to Achema, we promised you an exciting array of innovations. And at Bosch, we keep our promises!

It is no coincidence that our exhibition stand covers several hundred square meters here in Frankfurt. It is definitely worthwhile to spend some time with us in hall 3.1 over the next few days! Because as you know – and have come to expect from Bosch, we are presenting a number of new products and systems here at the trade show, including process and inspection technologies which significantly expand our portfolio.

Over the past few months you reported extensively about the acquisitions of Manesty, Hüttlin and Eisai Machinery. These acquisitions are important in several respects. On one hand, they reflect our presence along the entire value chain. At Bosch, this now extends from laboratory phases and pre-testing, to primary and secondary packaging, standalone machines and complete systems. On the other hand, we now serve the entire life cycle, from the development and installation of new machinery, to comprehensive services, upgrades and modernization of existing systems. Bosch operates in all of these segments with a wide range of products and services tailored to different markets and applications. The common denominators in this comprehensive portfolio are high quality and reliability. These attributes are consistently confirmed by our customers.

The 100th isolator manufactured and sold is a perfect example of how we integrate reliability, experience and knowledge to meet the needs of our customers.

For more than 20 years, Bosch Packaging Technology has been developing isolators for use in the pharmaceutical industry. Unlike conventional clean-room production systems, isolators ensure higher product quality, lower operating costs and reliable execution of longer production cycles. Our isolator systems are available for all types of machines used for filling ampoules, vials, cartridges and ready-to-use syringes. The 100th isolator will be used by a global pharmaceutical manufacturer in combination with a complete vial filling line for highly effective drugs.

These pharmaceuticals work wonders for patients. In production however, they pose a certain risk for machine operators. This is one more reason why we develop systems designed to ensure equal protection for workers and manufactured products.

The Fast Air Lock ISS 1000 is also designed to protect people and products. Developed for fast, contamination-free transfer of pharmaceutical equipment into and out of isolators, this new machine is being presented for the first time here in Frankfurt. Operating independently from the main filling isolator, the lock can be used for transferring microbiological materials or for other applications. Cycle times have been significantly reduced thanks to a highly efficient evaporation process and an optimized loading unit. Depending on the load, the ISS 1000 requires no more than approximately 20 minutes per cycle.

But I am not here to provide you with too much technical information – the details can be better demonstrated by the machinery on display at our booth. Like many of our products and systems, the ISS 1000 shows how we implement our fundamental system expertise to improve added value and efficiency for our customers.

Bosch system expertise is present across all business units and throughout the entire life cycle of our systems. Taking longevity a step further, our service portfolio has been consequently extended and thus, is far more comprehensive than it was decades ago. Today, in case of emergency for example a technician is available in a short period of time, delivering a solution from afar.

Mavus, our new mobile conferencing system, maximizes freedom of movement. It includes a headset with integrated camera, display, headphones and microphone. The rechargeable battery and electronics required for wireless data transmission are ergonomically and safely integrated into a vest. Mavus enables a technician on-site to make direct audio-visual contact with one of our experts. This may sound like a James Bond scenario, but when it comes to troubleshooting, a “guided expert” is in a position to access our consolidated technical knowledge within minutes.

At Bosch, technical knowledge and systems expertise already have an effect in the pre-production phase. We offer customers the chance to save resources by conducting lab experiments in our test labs using our machinery. Then the results can be reliably carried over to their in-house production systems.

At Achema, we are introducing two complete modular systems for laboratory use. Solidlab 1 and 2 are the results of a joint development by our process and technology specialists at Hüttlin and Manesty. One common base unit is all that is needed for the processing modules used for mixing, granulating and coating. This significantly lowers investment costs and reduces space requirements.

And this brings us back to the middle of the value chain. Consequently, here in Frankfurt we are presenting a complete process chain for dry pharmaceuticals consisting of different systems that map all process steps.

We recently initiated action to significantly build up our strength in one of these areas by taking over the entire Eisai Machinery portfolio of manual, semiautomatic and fully automatic inspection machines. This growth in so-called “process analytic technology” – or PAT for short – enhances the existing Bosch portfolio and fits extremely well into our overall strategy. It’s no coincidence that Eisai Machinery and Bosch Packaging Technology have worked together on numerous projects – the systems complement each other perfectly. Developments like our new, compact KKX 3900 inspection unit based on soft x-ray technology quickly bridge the gap to our Track & Trace solution for mass serialization. The pharmaceutical industry demands maximum process reliability along with effective protection against counterfeiting and manipulation – which result in far too many deaths in the world every day.

Close attention must be paid to the safety aspects in this industry – not only in mass production. Personalized medicine, for example drugs that are tailored to small, clearly profiled groups, is a rapidly growing trend.

For us, as system suppliers, this means smaller lot sizes and more frequent system changeovers – while paying close attention to hygiene aspects. This is where our new PreVAS product line comes into play. PreVAS stands for Pre-Validated, Pre-Assembled, Pre-Sterilized disposable filling system. A joint product from Bosch Packaging Technology and Sartorius Stedim Biotech, PreVAS will be implemented in this field on a long-term basis. PreVAS is also a perfect example of how close and diversified joint ventures have become commonplace in our industry. And this will need to continue if we want to keep pace with future market developments in line with the Bosch “Invented for life” commitment.

As you see, I could go on talking about the many new developments and applications in our portfolio. But an array of innovations is made to be seen, and not simply to be heard of. I invite you to use this opportunity to take a close up look at our systems presented here at the Achema show. Our experts will be happy to answer your questions – and we can get started right now.

The Bosch Group is a leading global supplier of technology and services. It employs roughly 375,000 associates worldwide (as of December 31, 2015). The company generated sales of 70.6 billion euros in 2015. Its operations are divided into four business sectors: Mobility Solutions, Industrial Technology, Consumer Goods, and Energy and Building Technology. The Bosch Group comprises Robert Bosch GmbH and its roughly 440 subsidiaries and regional companies in some 60 countries. Including sales and service partners, Bosch’s global manufacturing and sales network covers some 150 countries. The basis for the company’s future growth is its innovative strength. Bosch employs 55,800 associates in research and development at 118 locations across the globe. The Bosch Group’s strategic objective is to deliver innovations for a connected life. Bosch improves quality of life worldwide with products and services that are innovative and spark enthusiasm. In short, Bosch creates technology that is “Invented for life.”

The company was set up in Stuttgart in 1886 by Robert Bosch (1861-1942) as “Workshop for Precision Mechanics and Electrical Engineering.” The special ownership structure of Robert Bosch GmbH guarantees the entrepreneurial freedom of the Bosch Group, making it possible for the company to plan over the long term and to undertake significant up-front investments in the safeguarding of its future. Ninety-two percent of the share capital of Robert Bosch GmbH is held by Robert Bosch Stiftung GmbH, a charitable foundation. The majority of voting rights are held by Robert Bosch Industrietreuhand KG, an industrial trust. The entrepreneurial ownership functions are carried out by the trust. The remaining shares are held by the Bosch family and by Robert Bosch GmbH.

Additional information is available online at www.bosch.com and www.bosch-press.com, http://twitter.com/BoschPresse.

RF00160 - June 19, 2012

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