Stuttgart / Düsseldorf, Germany – At Interpack 2017, Bosch Packaging Technology presents new developments from its comprehensive portfolio for liquid pharmaceuticals. “We offer solutions and line concepts – from development and production through to filling, inspection, packaging and services, all featuring exceptionally high flexibility regarding products and packaging types,” says Christian Treitel, head of pharma business development at Bosch Packaging Technology.
From laboratory to production scale
The Bosch subsidiary Pharmatec already supports customers with suitable equipment during biotechnological drug production. The pilot fermenter on show at Interpack is suited for both laboratory and industrial manufacture of pilot batches for cell cultivation, for instance for the use in cancer medication. Thanks to different mixing technologies, it processes batches between eight and 50 liters. Via scale-up, batch sizes can even be increased to 200 liters.
New ALF 5000 stand-alone version for vials
For production-scale filling and closing of liquid pharmaceuticals Bosch showcases the ALF 5000 vial version for the first time. To date, customers could fill either ampoules or vials and ampoules on one machine. Now the proven platform is also available for vials only. The machine shown at Interpack is equipped with 100% in-process control and a carrying rake transport system, which provides an even gentler handling. The ALF 5000 achieves an output of up to 600 containers per minute and can be combined with different barrier systems – a competence, which Bosch also demonstrates at Interpack.
Comprehensive barrier competence
Apart from proven isolator technology and open Restricted Access Barrier Systems (RABS), closed RABS and the newly developed return air filter for highly potent products now complete the portfolio. In contrast to the commonly used safe change filters, which are situated in the technical area, the new return air filters are integrated into the machine. This saves time and facilitates cleaning, because the highly potent substances are already filtered at point-of-use. Moreover, the filter exchange is particularly easy and safe: there is no contact between the operator and the contaminated filter medium.
Containment and operator safety are also the focus of the downflow booth. Usually, the booth is used for manual weighing and dosing of powders. By supplying fresh air from the ceiling and drawing dust away from the operator, he can work with the substances in the closed space without safety concerns. As a tradeshow highlight, the downflow booth is converted into a meeting room for customers.
CCI portfolio completed
When it comes to the inspection of filled containers, Container Closure Integrity Testing (CCIT) is becoming increasingly important. With the KLV 1360, Bosch presents a new development for vacuum leak detection of rigid containers, which combines the highest inspection accuracy with maximum output. Together with fully automated solutions for high-volume leak detection and laser-based headspace analysis (HSA), Bosch can now offer an entire portfolio of CCI technologies. Benchtop devices for visual inspection, HSA and vacuum leak detection provide an additional overview of the broad inspection portfolio.
End-of-line assembly and packaging technology
The semi-automated MSA from the Bosch subsidiary Moeller & Devicon is designed for the assembly of multi-part single-use auto injectors or pens, which are used for the treatment of autoimmune diseases or in emergency care. With its compact and hygienic design, the MSA platform is suited for the assembly of small volumes between five and 15 pieces per minute. Thanks to standardized modules it can also be upgraded for larger batches and fully automated production, offering drug producers the flexibility to adapt quickly to new market demands.
Further technologies, such as product and equipment sterilization from the Bosch subsidiary Schoeller-Bleckmann Medizintechnik (SBM) complete the equipment portfolio for liquid pharmaceuticals. “We can provide customers with complete line concepts, tailored exactly to their requirements,” Christian Treitel says. These lines can be further extended by adding secondary packaging solutions, as well as platforms and industry 4.0 technologies for serialization and aggregation.
Customized services for all maintenance strategies
A comprehensive range of services to improve machine efficiency and productivity completes Bosch’s line competence. The focus is on solutions for preventive maintenance as well as services to eliminate unwanted machine conditions as quickly as possible. To this end, Bosch provides a worldwide service network with qualified field service technicians who offer regional support. Thanks to digital services such as Remote Service, which is now supported by a visualization and chat feature, or the mobile version of the E-Portal, which will be presented at Interpack 2017, customers receive targeted support regardless of their location. Bosch will further showcase the versatile training portfolio of the Bosch Packaging Academy. Apart from new assistance solutions, Bosch will demonstrate virtual training concepts enabling manufacturers to acquire demand-oriented know-how for machine operation and maintenance. Bosch will also illustrate how Preventive Maintenance Parts Kits and tailor-made maintenance agreements help to proactively minimize unplanned downtime.
Bosch at Interpack: hall 6, booth A30-C58
phone: +49 7951 402-875
Contact person for press inquiries:
phone: +49 7951 402-648
Based in Waiblingen near Stuttgart, Germany, and employing 6,200 associates, the Bosch Packaging Technology division is one of the leading suppliers of process and packaging technology. At over 30 locations in more than 15 countries worldwide, a highly-qualified workforce develops and produces complete solutions for the pharmaceuticals, food, and confectionery industries. These solutions are complemented by a comprehensive after-sales service portfolio. A global service and sales network provides customers with local points of contact.
Additional information is available online at www.boschpackaging.com
The Bosch Group is a leading global supplier of technology and services. It employs roughly 390,000 associates worldwide (as of December 31, 2016). According to preliminary figures, the company generated sales of 73.1 billion euros in 2016. Its operations are divided into four business sectors: Mobility Solutions, Industrial Technology, Consumer Goods, and Energy and Building Technology. As a leading IoT company, Bosch offers innovative solutions for smart homes, smart cities, connected mobility, and connected industry. It uses its expertise in sensor technology, software, and services, as well as its own IoT cloud, to offer its customers connected, cross-domain solutions from a single source. The Bosch Group’s strategic objective is to create solutions for a connected life, and to improve quality of life worldwide with products and services that are innovative and spark enthusiasm. In short, Bosch creates technology that is “Invented for life.” The Bosch Group comprises Robert Bosch GmbH and its roughly 450 subsidiaries and regional companies in some 60 countries. Including sales and service partners, Bosch’s global manufacturing, engineering, and sales network covers nearly every country in the world. The basis for the company’s future growth is its innovative strength. At 120 locations across the globe, Bosch employs 59,000 associates in research and development.